Our current 44 research projects (see full list below) fall into two areas. In Sperm Biology we use experimental evolution and other experimental approaches to understand the significance of environmental (aka lifestyle) effects on sperm function, including infections, diet or atmospheric variation. Of central importance are oxygen radicals and sperm metabolism, which we measure using laser-induced fluorescence microscopy FLIM and microfluometry. See also Biz Turnell‘s, Barbara Eckel‘s, Conni Wetzker‘s, Ruijian Guo‘s and Klaus Reinhardt‘ page.
In Mito-nuclear interactions we focus on mitochondria, our cells’ powerhouses. The interaction of mitochondrial DNA with chromosomal DNA has substantial implications for the so-called mitochondrial replacement therapy (three-parent-baby technology). We aim to combine genetic methods with experimental evolution in order to identify suitable mito-nuclear interactions. See also Ralph Dobler‘s, Susanne Voigt’s, Ruijian Guo‘s and Klaus Reinhardt‘s page.
List of current projects (finalised projects: see Publications):